Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri

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Platelet Septic Transfusion Reactions in Patients With Hemato-Oncological Diseases

Background & Objective: Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable conditions for the proliferation of microorganisms....

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Platelet Septic Transfusion Reactions in Patients With Hemato-Oncological Diseases

Background & Objective Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable conditions for the proliferation of microorganisms.The current study aimed at investigating the trans...

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Antigenic scheme of Citrobacter koseri.

An antigenic scheme, based on the determination of 17 somatic and 9 flagellar antigens, is proposed for Citrobacter koseri. Seven of the flagellar antigens constituted the specific phase (a through g), and the others (1 and 2) were nonspecific. Of the 238 theoretically possible serotypes, 48 were identified among 680 cultures examined.

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How do I investigate septic transfusion reactions and blood donors with culture-positive platelet donations?

I n the early 1990s, bacterial contamination of blood components was recognized as the most common cause of transfusion-transmitted infection, accounting for between 14 and 24% of transfusion associated fatalities reported to the US Food and Drug Administration and various hemovigilance systems. Because platelets (PLTs) are stored at room temperature, they provide a hospitable environment for t...

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ژورنال

عنوان ژورنال: Annals of Blood

سال: 2020

ISSN: 2521-361X

DOI: 10.21037/aob-20-41